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Home NFL Sportsbooks quickly released betting lines for the 2026 NFL season opener, featuring a Super Bowl rematch and the league's first game in Australia.
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NFL's 2026 Week 1 Opening Lines Posted as Schedule Goes Live

Sportsbooks quickly released betting lines for the 2026 NFL season opener, featuring a Super Bowl rematch and the league's first game in Australia.

🕒 Last Updated: 2026-05-15 3:46pm EDT

Sportsbooks moved fast. Within hours of the NFL releasing its 2026 schedule, betting lines went live for opening week.

The slate is stacked: a Super Bowl rematch between the Seahawks and Patriots kicks off Wednesday night, followed by the NFL's first-ever game in Australia featuring the Rams and 49ers. Sixteen matchups across four days set the tone for the season.

Here are the opening odds from DraftKings Sportsbook as of May 15:

Wednesday, Sept. 9

Patriots @ Seahawks

  • Spread: Seahawks -3.5
  • Moneyline: Seahawks -205, Patriots +170
  • O/U: 44.5

Thursday, Sept. 10

49ers @ Rams (Australia)

  • Spread: Rams -2.5
  • Moneyline: Rams -155, 49ers +130
  • O/U: 48.5

Sunday, Sept. 13

Saints @ Lions

  • Spread: Lions -7
  • Moneyline: Lions -325, Saints +260
  • O/U: 48.5

Bears @ Panthers

  • Spread: Bears -2.5
  • Moneyline: Bears -135, Panthers +114
  • O/U: 44.5

Ravens @ Colts

  • Spread: Ravens -3.5
  • Moneyline: Ravens -185, Colts +154
  • O/U: 49.5

Bills @ Texans

  • Spread: Bills -1.5
  • Moneyline: Bills -112, Texans -108
  • O/U: 45.5

Falcons @ Steelers

  • Spread: Steelers -3
  • Moneyline: Steelers -175, Falcons +145
  • O/U: 42.5

Buccaneers @ Bengals

  • Spread: Bengals -3.5
  • Moneyline: Bengals -198, Buccaneers +164
  • O/U: 50.5

Browns @ Jaguars

  • Spread: Jaguars -7
  • Moneyline: Jaguars -285, Browns +230
  • O/U: 40.5

Jets @ Titans

  • Spread: Titans -3
  • Moneyline: Titans -170, Jets +142
  • O/U: 39.5

Commanders @ Eagles

  • Spread: Eagles -5.5
  • Moneyline: Eagles -238, Commanders +195
  • O/U: 46.5

Packers @ Vikings

  • Spread: Packers -1.5
  • Moneyline: Packers -125, Vikings +105
  • O/U: 44.5

Cardinals @ Chargers

  • Spread: Chargers -11.5
  • Moneyline: Chargers -625, Cardinals +455
  • O/U: 45.5

Dolphins @ Raiders

  • Spread: Raiders -3
  • Moneyline: Raiders -180, Dolphins +150
  • O/U: 41.5

Cowboys @ Giants

  • Spread: Cowboys -2.5
  • Moneyline: Cowboys -130, Giants +110
  • O/U: 48.5

Monday, Sept. 14

Broncos @ Chiefs

  • Spread: Chiefs -2.5
  • Moneyline: Chiefs -155, Broncos +130
  • O/U: 42.5

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