Three marquee matchups on Thursday and Friday will draw massive wagering volume as the nation settles in for family, food, and football.

The NFL's Thanksgiving slate features Packers-Lions at 1 p.m. ET on FOX, Chiefs-Cowboys at 4:30 p.m. ET, and Bengals-Ravens at 8:20 p.m. ET—a trio of games that figures to command unprecedented betting attention.

"Thanksgiving is turkey and football. That's how it is in the United States," said Joey Feazel, head of football trading at Caesars Sports. "Everybody is home, nobody's working. A lot of people are really homing in on those three football games. The first game of the season is often the most-bet game of the year, or at least top five. These Thanksgiving games will be right up there with that or even a playoff-type game."

Packers-Lions: Sharp Money on Green Bay

The Lions (8-4 SU, 7-5 ATS) opened as 3-point home favorites, but early action on the Packers (+3) shifted the line to Lions -2.5, where it remained Wednesday afternoon. Green Bay sits at 7-3-1 SU but a struggling 4-7 ATS.

Feazel noted that while the action has been "pretty one-sided on the Lions," sharp bettors grabbed Packers +3 early in the week.

"The Packers are not as explosive offensively as Detroit, and people gravitate to scoring. So we'll be rooting for a close, low-scoring game."

The total opened at 49.5 and has fluctuated between 49.5 and 48.5, settling at 48.5 on Wednesday afternoon. Expect heavy public money on the Over across all three Thanksgiving games.

Chiefs-Cowboys: The Year's Biggest Betting Event

This matchup sits atop the Thanksgiving card as a potential record-breaker for wagering volume. Kansas City opened as a 4.5-point road favorite but has settled at Chiefs -3.5 after early Dallas action pushed it as low as -3.

Professional bettor Randy McKay is backing Under 52.5, citing Dallas's improved defense under coordinator Matt Eberflus and Kansas City's clock-consuming offensive approach.

"Dallas is greatly improved on defense and getting more used to defensive coordinator Matt Eberflus' adjustments. Kansas City isn't an explosive team. They score with long, clock-consuming drives. On the other side, Dallas has offensive line injuries, vs. a very good K.C. defense led by Chris Jones."

Cowboys left tackle Tyler Guyton is doubtful with a high ankle sprain, a critical blow to Dallas's protection schemes.

Feazel emphasized the magnitude of this game:

"One thing we've noticed this year is that Cowboys games are driving a lot of action. The Chiefs also drive a lot of action, whether for or against. So this should be one of the biggest-bet games of the year."

Bengals-Ravens: Burrow's Return Reshapes the Line

Cincinnati's Joe Burrow—sidelined since a Week 2 toe injury—is expected to return Thursday night, dramatically altering the betting landscape. The Ravens (6-5 SU, 5-6 ATS) opened as 10-point favorites on the lookahead line, but Burrow's anticipated availability prompted a 3-point swing toward the Bengals, settling the line at Ravens -7.

The Bengals (3-8 SU, 4-7 ATS) have lost four consecutive games while Baltimore enters on a five-game winning streak.

"The point spread is really reflecting that. Burrow starting was baked into that number," Feazel said. "So far, bettors are on the Bengals a little bit. But I think it'll be a little more balanced by game time, two-way action. The need will probably be for a lower-scoring game. I anticipate a lot of money on the Over, and a lot of same-game parlays. Neither defense has played well, and all the stars are on the same side of the ball."

Bookmakers will likely need an Under and Ravens win to offset heavy public backing of the Over and same-game parlays.

Black Friday: Bears Stun, Eagles Fade

The Bears (8-3 SU, 6-4-1 ATS) sit atop the NFC North despite preseason pessimism. The Eagles (8-3 SU, 7-4 ATS) are licking wounds after a catastrophic collapse at Dallas—squandering a 21-0 lead in a 24-21 loss.

Caesars opened Philadelphia as a 7-point home favorite for Friday's 3 p.m. ET kickoff. The line briefly dipped to -6.5 Wednesday morning before returning to -7.

"This is another game that will drive a lot of action. Bettors have not been attracted to the Eagles lately, and we're seeing that here. People are starting to buy in a little more on the Bears. There's a lot of Bears point-spread and moneyline action. But I expect we'll see some Eagles action by game time. We'll probably need an Eagles win and a Bears cover."

Sunday's Steeltown Showdown

Buffalo (7-4 SU, 5-6 ATS) and Pittsburgh (6-5 SU, 6-4-1 ATS) both show troubling recent form. The Bills are 3-4 SU and ATS over their last seven games after losing two of three. Pittsburgh started 4-1 but has cratered since.

Caesars opened Buffalo as a 4.5-point road favorite but the line has settled at Bills -3.5, with Buffalo attracting the bulk of action despite underwhelming performance.

"Bettors are still coming in on the Bills, even though they haven't lived up to expectations. So it's mostly Bills action, and we anticipate a lot more Bills money coming in closer to game time," Feazel said.

Notable Bets

A DraftKings customer netted $41,666.67 in profit by wagering $45,000 on 49ers -7.5 against Carolina, pocketing an $86,666.67 total when San Francisco won 20-9.

Meanwhile, a Caesars Sports bettor placed $500 on Broncos QB Bo Nix at +10000 odds (100/1) to win NFL MVP. Nix sits 11th in MVP odds, well behind favorite Rams QB Matthew Stafford (-230). A $50,000 payday awaits if the rookie engineers an unprecedented six-game surge.

Wager responsibly. Never bet more than you can afford to lose.